Keyword: Snake / Aquarius / O / Koara / I was born in Numazu and grew up in Shizuoka
蛇年 / 水瓶座 / O型 / コアラ / 沼津生まれの静岡育ち

I am a professor of Graduate School of Informatics, Nagoya University.
I would like to enjoy my life and scientific research as much as I can.

研究も生活も，楽しみたいと思っています．

Major 専門

• Biophysics 生物物理学
• Bioinformatics 生命情報学

Especially 特に

Structural Bioinformatics 構造バイオインフォマティクス

Structural Bioinfomatics examines biological phenomena based on the tertiary structure of proteins or nucleic acids by means of computational way, instead of experiments

構造バイオインフォマティクスはタンパク質や核酸の立体構造に基づく生物学です．実験はやらず，主に計算機を使います.

Research Interests 研究テーマ

• Protein complexes タンパク質複合体
• Protein-protein interactions タンパク質の相互作用
• Protein folding タンパク質のフォールディング
• Intrinsically disordered protein 天然変性タンパク質
• Protein structure prediction タンパク質の立体構造予測
• Protein design タンパク質のデザイン
• Comparative genomics 比較ゲノム
• Systems biology システムバイオロジー

Education / Employments 学歴と職歴

• 1990 M. S. Waseda University (Applied Physics, Aizawa Laboratory) 早稲田大学大学院修士課程修了
• 1990 Researcher, Tonen Corporation 東燃株式会社
• 1994 Researcher, Protein Engineering Research Institute （株）蛋白工学研究所
• 1996 JSPS Research Fellow 日本学術振興会特別研究員
• 1996 Ph. D. Waseda University (Applied Physics, Aizawa Laboratory) 早稲田大学大学院博士課程修了
• 1996 Assistant Professor, National Institute of Genetics (CIB-DDBJ) 国立遺伝学研究所助手
• 2002 Associate Professor, Tokyo Institute of Technology (GSIC) 東京工業大学助教授
• 2008 Professor, Nagoya University (Grad. Sch. Info.) 名古屋大学教授

Selected Papers 主要論文

• M. Ota, H. Gonja, R. Koike, S. Fukuchi.
  Multiple-localization and hub proteins. PLos One (2016) 11, e0156455, pubmed
• R. Koike, M. Ota, A. Kidera.
  Hierarchical description and extensive classification of protein structural changes by Motion Tree. J. Mol. Biol. (2014) 426, 752-762, pubmed
• S. Fukuchi, T. Amemiya, S.Sakamoto, Y. Nobe, K. Hosoda, Y. Kado, SD. Murakami, R. Koike, H. Hiroaki, M. Ota.
  IDEAL in 2014 illustrates interaction networks composed of intrinsically disordered proteins and their binding partners. Nucleic Acids Res. (2014) 42, D320-D325, pubmed
• R. Koike, M. Ota.
  SCPC: a method to structurally compare protein complexes. Bioinformatics (2012) 28, 324-330, pubmed
• Y. Isogai Y. Ito, T. Ikeya, Y. Shiro, M. Ota.
  Design of λCro fold: solution structure of a monomeric variant of the de novo protein. J. Mol. Biol. (2005) 354, 801-814, pubmed
• M. Ota, M. Ikeguchi, A. Kidera.
  Phylogeny of protein-folding trajectories reveals a unique pathway to native structure. Proc. Natl. Acad. Sci. USA (2004) 101, 17658-17663, pubmed
• M. Ota, K. Kinoshita, K. Nishikawa.
  Prediction of catalytic residues in enzymes based on known tertiary structure, stability profile, and sequence conservation. J. Mol. Biol. (2003) 327, 1053-1064, pubmed
• M. Ota, T. Kawabata, AR. Kinjo, K. Nishikawa.
  Cooperative approach for the protein fold recognition. Proteins (1999) suppl.3, 126-132, pubmed
• M. Ota, S. Kanaya, K. Nishikawa.
  Desk-top analysis of the structural stabilities of various point mutations introduced into ribonuclease H. J. Mol. Biol. (1995) 248, 733-738, pubmed

  Motonori Ota - Google Scholer

  

My Favorite Things お気に入り

• Jazz music
  Michael Brecker, David Liebman, Wayne Shorter, Jaco Pastorius, Toots Thielemans, Chick Corea, Baden Powell, Karen Carpenter
• Art
  Maurice Utrillo, Egon Schiele, Joan Miró, Andy Warhol, Itō Jakuchū 伊藤 若冲
• Movies
  Pierrot Le Fou 気狂いピエロ, El Topo エルトポ, A Crockwise Orange 時計仕掛けのオレンジ, Savage Messah 狂えるメサイア, Annie Hall アニーホール
• Books
  Haruki Murakami 村上春樹, Natsuo Kirino 桐野夏生, Kazuo Ishiguro カズオ イシグロ, Yoshiharu Tsuge つげ義春, NARUTO
• Restaurants
  Curry カレー: Mu-min 夢民, Erick south エリックサウス
  Eel 鰻: Unashige うな繁, Suisen en 水泉園
  Sea food 海鮮: Kira きら, Isaribi Shokudo いさりび食堂
  Ramen ラーメン: Matchi bo まっち棒, Shichi Sai 七彩, Mitake みたけ
  Italian, Spanish 西洋系: El Pescador, ARAGUSA
  
• Foot ball
  Shimizu s-puls 清水エスパルス
• Hot spring 温泉
Do-ga shima 堂ヶ島, Shirako 白子